CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family

Enzyme Information

2.8.2.37
Trehalose 2-sulfotransferase.
based on mapping to UniProt P84151
3'-phosphoadenylyl sulfate + alpha,alpha-trehalose = adenosine 3',5'-bisphosphate + 2-O-sulfo-alpha,alpha-trehalose.
-!- The sulfation of trehalose in the bacterium Mycobacterium tuberculosis is required for the biosynthesis of sulfolipid-1.

UniProtKB Entries (1)

P84151
P84151_MYCSM
Mycolicibacterium smegmatis
Putative sulfotransferase

PDB Structure

PDB 1TEX
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Identification, function and structure of the mycobacterial sulfotransferase that initiates sulfolipid-1 biosynthesis.
Mougous, J.D., Petzold, C.J., Senaratne, R.H., Lee, D.H., Akey, D.L., Lin, F.L., Munchel, S.E., Pratt, M.R., Riley, L.W., Leary, J.A., Berger, J.M., Bertozzi, C.R.
Nat.Struct.Mol.Biol.