CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.300 | P-loop containing nucleotide triphosphate hydrolases |
Domain Context
CATH Clusters
| Superfamily | P-loop containing nucleotide triphosphate hydrolases |
| Functional Family | Guanine nucleotide-binding protein G(k) subunit alpha |
Enzyme Information
UniProtKB Entries (3)
| P10824 |
GNAI1_RAT
Rattus norvegicus
Guanine nucleotide-binding protein G(i) subunit alpha-1
|
| P27601 |
GNA13_MOUSE
Mus musculus
Guanine nucleotide-binding protein subunit alpha-13
|
| Q92888 |
ARHG1_HUMAN
Homo sapiens
Rho guanine nucleotide exchange factor 1
|
PDB Structure
| PDB | 1SHZ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structure of the p115RhoGEF rgRGS domain-Galpha13/i1 chimera complex suggests convergent evolution of a GTPase activator.
Nat.Struct.Mol.Biol.
|