CATH Classification

Domain Context

CATH Clusters

Superfamily Hotdog Thioesterase
Functional Family 1,4-dihydroxy-2-naphthoyl-CoA hydrolase

Enzyme Information

3.1.2.28
1,4-dihydroxy-2-naphthoyl-CoA hydrolase.
based on mapping to UniProt P77781
1,4-dihydroxy-2-naphthoyl-CoA + H(2)O = 1,4-dihydroxy-2-naphthoate + CoA.
-!- This enzyme participates in the synthesis of menaquinones, phylloquinone, as well as several plant pigments. -!- The enzyme from the cyanobacterium Synechocystis sp. PCC 6803 does not accept benzoyl-CoA or phenylacetyl-CoA as substrates. -!- Formerly EC 3.1.2.n1.

UniProtKB Entries (1)

P77781
MENI_ECOLI
Escherichia coli K-12
1,4-dihydroxy-2-naphthoyl-CoA hydrolase

PDB Structure

PDB 1SBK
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
X-ray Structure of YDII_ECOLI Northeast Structural Genomics Consortium Target ER29
Kuzin, A.P., Edstrom, W., Vorobiev, S.M., Lee, I., Forouhar, F., Ma, L., Chiang, Y., Rong, X., Acton, T.B., Montelione, G.T., Hunt, J.F., Tong, L.
To be Published