CATH Classification

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family Cytochrome b2, mitochondrial, putative

Enzyme Information

1.1.2.3
L-lactate dehydrogenase (cytochrome).
based on mapping to UniProt P00175
(S)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c + 2 H(+).

UniProtKB Entries (1)

P00175
CYB2_YEAST
Saccharomyces cerevisiae S288C
Cytochrome b2, mitochondrial

PDB Structure

PDB 1QCW
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Kinetic and crystallographic studies on the active site Arg289Lys mutant of flavocytochrome b2 (yeast L-lactate dehydrogenase)
Mowat, C.G., Beaudoin, I., Durley, R.C.E., Barton, J.D., Pike, A.D., Chen, Z.-W., Reid, G.A., Chapman, S.K., Mathews, F.S., Lederer, F.
Biochemistry