CATH Classification

Domain Context

CATH Clusters

Superfamily Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family General transcription factor IIH subunit 1

Enzyme Information

UniProtKB Entries (1)

P32780
TF2H1_HUMAN
Homo sapiens
General transcription factor IIH subunit 1

PDB Structure

PDB 1PFJ
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
TFIIH contains a PH domain involved in DNA nucleotide excision repair.
Gervais, V., Lamour, V., Jawhari, A., Frindel, F., Wasielewski, E., Dubaele, S., Egly, J.M., Thierry, J.C., Kieffer, B., Poterszman, A.
Nat.Struct.Mol.Biol.