CATH Classification

Domain Context

CATH Clusters

Superfamily Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family Non-specific serine/threonine protein kinase

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt P31751
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

P31751
AKT2_HUMAN
Homo sapiens
RAC-beta serine/threonine-protein kinase

PDB Structure

PDB 1P6S
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
Solution structure and backbone dynamics of the pleckstrin homology domain of the human protein kinase B (PKB/Akt). Interaction with inositol phosphates.
Auguin, D., Barthe, P., Auge-Senegas, M.T., Stern, M.H., Noguchi, M., Roumestand, C.
J.BIOMOL.NMR