CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family KRAS proto-oncogene, GTPase

Enzyme Information

UniProtKB Entries (1)

Q07889
SOS1_HUMAN
Homo sapiens
Son of sevenless homolog 1

PDB Structure

PDB 1NVU
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS
Margarit, S.M., Sondermann, H., Hall, B.E., Nagar, B., Hoelz, A., Pirruccello, M., Bar-Sagi, D., Kuriyan, J.
Cell(Cambridge,Mass.)