CATH Classification

Domain Context

CATH Clusters

Superfamily Glycosidases
Functional Family Beta-hexosaminidase A

Enzyme Information

3.2.1.52
Beta-N-acetylhexosaminidase.
based on mapping to UniProt P07686
Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.
-!- Acts on N-acetylglucosides and N-acetylgalactosides. -!- Formerly EC 3.2.1.29 and EC 3.2.1.30.

UniProtKB Entries (1)

P07686
HEXB_HUMAN
Homo sapiens
Beta-hexosaminidase subunit beta

PDB Structure

PDB 1NOW
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of Human beta-hexosaminidase B: Understanding the molecular basis of Sandhoff and Tay-Sachs disease
Mark, B.L., Mahuran, D.J., Cherney, M.M., Zhao, D., Knapp, S., James, M.N.G.
J.Mol.Biol.