CATH Classification

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family

Enzyme Information

1.1.1.205
IMP dehydrogenase.
based on mapping to UniProt P50097
Inosine 5'-phosphate + NAD(+) + H(2)O = xanthosine 5'-phosphate + NADH.
-!- The enzyme acts on the hydroxy group of the hydrated derivative of the substrate. -!- Formerly EC 1.2.1.14.

UniProtKB Entries (1)

P50097
IMDH_TRIFO
Tritrichomonas suis
Inosine-5'-monophosphate dehydrogenase

PDB Structure

PDB 1ME9
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal Structures of Tritrichomonas foetus Inosine Monophosphate Dehydrogenase in Complex with Substrate, Cofactor and Analogs: A Structural Basis for the Random-in Ordered-out Kinetic Mechanism
Prosise, G.L., Luecke, H.
J.Mol.Biol.