CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family Estrogen sulfotransferase

Enzyme Information

2.8.2.1
Aryl sulfotransferase.
based on mapping to UniProt P50225
3'-phosphoadenylyl sulfate + a phenol = adenosine 3',5'-bisphosphate + an aryl sulfate.
-!- A number of aromatic compounds can act as acceptors. -!- Organic hydroxylamines are not substrates (cf. EC 2.8.2.9).

UniProtKB Entries (1)

P50225
ST1A1_HUMAN
Homo sapiens
Sulfotransferase 1A1

PDB Structure

PDB 1LS6
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of a human carcinogen-converting enzyme, SULT1A1. Structural and kinetic implications of substrate inhibition.
Gamage, N.U., Duggleby, R.G., Barnett, A.C., Tresillian, M., Latham, C.F., Liyou, N.E., McManus, M.E., Martin, J.L.
J.Biol.Chem.