CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.30 | Roll |
|
2.30.29 | PH-domain like |
|
2.30.29.30 | Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) |
Domain Context
CATH Clusters
| Superfamily | Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) |
| Functional Family | Guanine nucleotide exchange factor DBS |
Enzyme Information
UniProtKB Entries (2)
| Q64096 |
MCF2L_MOUSE
Mus musculus
Guanine nucleotide exchange factor DBS
|
| P61586 |
RHOA_HUMAN
Homo sapiens
Transforming protein RhoA
|
PDB Structure
| PDB | 1LB1 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structural basis for the selective activation of Rho GTPases by Dbl exchange factors.
Nat.Struct.Biol.
|