1 keywords

CATH Domain 1l6xA01

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.40 Immunoglobulin-like
Homologous Superfamily 2.60.40.10 Immunoglobulins

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family Immunoglobulin heavy constant gamma 1

Enzyme Information

UniProtKB Entries (1)

P01857
IGHG1_HUMAN
Homo sapiens
Immunoglobulin heavy constant gamma 1

PDB Structure

PDB 1L6X
External Links
Method X-RAY DIFFRACTION
Organism Cricetulus
Primary Citation
Mapping of the C1q binding site on rituxan, a chimeric antibody with a human IgG1 Fc.
Idusogie, E.E., Presta, L.G., Gazzano-Santoro, H., Totpal, K., Wong, P.Y., Ultsch, M., Meng, Y.G., Mulkerrin, M.G.
J.Immunol.