CATH Classification

Domain Context

CATH Clusters

Superfamily ATP-grasp fold, B domain
Functional Family Succinate--CoA ligase [ADP-forming] subunit beta

Enzyme Information

6.2.1.5
Succinate--CoA ligase (ADP-forming).
based on mapping to UniProt P0A836
ATP + succinate + CoA = ADP + phosphate + succinyl-CoA.

UniProtKB Entries (1)

P0A836
SUCC_ECOLI
Escherichia coli K-12
Succinate--CoA ligase [ADP-forming] subunit beta

PDB Structure

PDB 1JLL
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Two glutamate residues, Glu 208 alpha and Glu 197 beta, are crucial for phosphorylation and dephosphorylation of the active-site histidine residue in succinyl-CoA synthetase.
Fraser, M.E., Joyce, M.A., Ryan, D.G., Wolodko, W.T.
Biochemistry