CATH Classification

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family

Enzyme Information

2.5.1.55
3-deoxy-8-phosphooctulonate synthase.
based on mapping to UniProt O66496
Phosphoenolpyruvate + D-arabinose 5-phosphate + H(2)O = 3-deoxy-D-manno- octulosonate 8-phosphate + phosphate.
-!- Formerly EC 4.1.2.16.

UniProtKB Entries (1)

O66496
KDSA_AQUAE
Aquifex aeolicus VF5
2-dehydro-3-deoxyphosphooctonate aldolase

PDB Structure

PDB 1JCX
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structures of Aquifex aeolicus KDO8P synthase in complex with R5P and PEP, and with a bisubstrate inhibitor: role of active site water in catalysis.
Wang, J., Duewel, H.S., Woodard, R.W., Gatti, D.L.
Biochemistry