CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.70 | Aldolase class I |
Domain Context
CATH Clusters
| Superfamily | Aldolase class I |
| Functional Family | Inosine-5'-monophosphate dehydrogenase 2 |
Enzyme Information
| 1.1.1.205 |
IMP dehydrogenase.
based on mapping to UniProt P20839
Inosine 5'-phosphate + NAD(+) + H(2)O = xanthosine 5'-phosphate + NADH.
-!- The enzyme acts on the hydroxy group of the hydrated derivative of the substrate. -!- Formerly EC 1.2.1.14.
|
UniProtKB Entries (1)
| P20839 |
IMDH1_HUMAN
Homo sapiens
Inosine-5'-monophosphate dehydrogenase 1
|
PDB Structure
| PDB | 1JCN |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal Structure of the Human Type I Inosine Monophosphate Dehydrogenase and Implications for Isoform Specificity
To be Published
|