CATH Classification

Domain Context

CATH Clusters

Superfamily Periplasmic binding protein-like II
Functional Family ATP phosphoribosyltransferase

Enzyme Information

2.4.2.17
ATP phosphoribosyltransferase.
based on mapping to UniProt P60757
1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate = ATP + 5-phospho-alpha-D- ribose 1-diphosphate.
-!- Involved in histidine biosynthesis.

UniProtKB Entries (1)

P60757
HIS1_ECOLI
Escherichia coli K-12
ATP phosphoribosyltransferase

PDB Structure

PDB 1H3D
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The Structure of Escherichia Coli ATP-Phosphoribosyltransferase: Identification of Substrate Binding Sites and Mode of AMP Inhibition
Lohkamp, B., Mcdermott, G., Campbell, S., Coggins, J.R., Lapthorn, A.J.
J.Mol.Biol.