CATH Classification

Domain Context

CATH Clusters

Superfamily SH3 Domains
Functional Family Tyrosine-protein kinase

Enzyme Information

2.7.10.2
Non-specific protein-tyrosine kinase.
based on mapping to UniProt P24604
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
-!- Unlike EC 2.7.10.1, this protein-tyrosine kinase does not have a transmembrane domain. -!- In the human genome, 32 non-specific protein-tyrosine kinases have been identified and these can be divided into 10 families. -!- Formerly EC 2.7.1.112.

UniProtKB Entries (1)

P24604
TEC_MOUSE
Mus musculus
Tyrosine-protein kinase Tec

PDB Structure

PDB 1GL5
External Links
Method SOLUTION NMR
Organism
Primary Citation
The solution structure and intramolecular associations of the Tec kinase SRC homology 3 domain.
Pursglove, S.E., Mulhern, T.D., Mackay, J.P., Hinds, M.G., Booker, G.W.
J. Biol. Chem.