CATH Classification

CATH Clusters

Superfamily Immunoglobulins
Functional Family Protein-glutamine gamma-glutamyltransferase 5

Enzyme Information
Protein-glutamine gamma-glutamyltransferase.
based on mapping to UniProt P00488
Protein glutamine + alkylamine = protein N(5)-alkylglutamine + NH(3).
-!- The gamma-carboxymide groups of peptide-bound glutamine residues act as acyl donors, and the 6-amino-groups of protein- and peptide-bound lysine residues act as acceptors, to give intra- and inter-molecular N(6)-(5-glutamyl)lysine crosslinks.

UniProtKB Entries (1)

Homo sapiens
Coagulation factor XIII A chain

PDB Structure

PDB 1F13
External Links
Organism Saccharomyces
Primary Citation
Two non-proline cis peptide bonds may be important for factor XIII function.
Weiss, M.S., Metzner, H.J., Hilgenfeld, R.
FEBS Lett.