CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.300 | P-loop containing nucleotide triphosphate hydrolases |
Domain Context
CATH Clusters
| Superfamily | P-loop containing nucleotide triphosphate hydrolases |
| Functional Family |
Enzyme Information
| 2.7.4.8 |
Guanylate kinase.
based on mapping to UniProt P15454
ATP + GMP = ADP + GDP.
-!- dGMP can also act as acceptor. -!- dATP can act as donor.
|
UniProtKB Entries (1)
| P15454 |
KGUA_YEAST
Saccharomyces cerevisiae S288C
Guanylate kinase
|
PDB Structure
| PDB | 1EX6 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of unligated guanylate kinase from yeast reveals GMP-induced conformational changes.
J.Mol.Biol.
|