CATH Classification

Domain Context

CATH Clusters

Superfamily Periplasmic binding protein-like II
Functional Family Serotransferrin

Enzyme Information

UniProtKB Entries (1)

P02787
TRFE_HUMAN
Homo sapiens
Serotransferrin

PDB Structure

PDB 1DTG
External Links
Method X-RAY DIFFRACTION
Organism Mesocricetus
Primary Citation
Mutation of the iron ligand His 249 to Glu in the N-lobe of human transferrin abolishes the dilysine "trigger" but does not significantly affect iron release.
MacGillivray, R.T., Bewley, M.C., Smith, C.A., He, Q.Y., Mason, A.B.
Biochemistry