CATH Classification

Domain Context

CATH Clusters

Superfamily Dihydrodipicolinate Reductase; domain 2
Functional Family Glyceraldehyde-3-phosphate dehydrogenase

Enzyme Information

1.2.1.12
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).
based on mapping to UniProt P0A9B2
D-glyceraldehyde 3-phosphate + phosphate + NAD(+) = 3-phospho-D-glyceroyl phosphate + NADH.
-!- Also acts very slowly on D-glyceraldehyde and some other aldehydes. -!- Thiols can replace phosphate.

UniProtKB Entries (1)

P0A9B2
G3P1_ECOLI
Escherichia coli K-12
Glyceraldehyde-3-phosphate dehydrogenase A

PDB Structure

PDB 1DC3
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural analysis of glyceraldehyde 3-phosphate dehydrogenase from Escherichia coli: direct evidence of substrate binding and cofactor-induced conformational changes.
Yun, M., Park, C.G., Kim, J.Y., Park, H.W.
Biochemistry