CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.2300
Functional Family Low molecular weight phosphotyrosine protein

Enzyme Information

3.1.3.2
Acid phosphatase.
based on mapping to UniProt P40347
A phosphate monoester + H(2)O = an alcohol + phosphate.
-!- Wide specificity. -!- Also catalyzes transphosphorylations.
3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt P40347
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

P40347
PPAL_YEAST
Saccharomyces cerevisiae S288C
Low molecular weight phosphotyrosine protein phosphatase

PDB Structure

PDB 1D1P
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structures of a low-molecular weight protein tyrosine phosphatase from Saccharomyces cerevisiae and its complex with the substrate p-nitrophenyl phosphate.
Wang, S., Tabernero, L., Zhang, M., Harms, E., Van Etten, R.L., Stauffacher, C.V.
Biochemistry