CATH Classification

Domain Context

CATH Clusters

Superfamily Glycosidases
Functional Family

Enzyme Information

3.2.1.4
Cellulase.
based on mapping to UniProt P0C2S3
Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.
-!- Will also hydrolyze 1,4-linkages in beta-D-glucans also containing 1,3-linkages.

UniProtKB Entries (1)

P0C2S3
GUNC_CLOTM
Hungateiclostridium thermocellum
Endoglucanase C

PDB Structure

PDB 1CEN
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The crystal structure of a family 5 endoglucanase mutant in complexed and uncomplexed forms reveals an induced fit activation mechanism.
Dominguez, R., Souchon, H., Lascombe, M., Alzari, P.M.
J.Mol.Biol.