CATH Classification

Domain Context

CATH Clusters

Superfamily Glycosidases
Functional Family

Enzyme Information

3.2.1.96
Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase.
based on mapping to UniProt P04067
Endohydrolysis of the N,N'-diacetylchitobiosyl unit in high-mannose glycopeptides and glycoproteins containing the -(Man(GlcNAc)(2))Asn- structure. One N-acetyl-D-glucosamine residue remains attached to the protein, the rest of the oligosaccharide is released intact.

UniProtKB Entries (1)

P04067
EBAG_STRPL
Streptomyces plicatus
Endo-beta-N-acetylglucosaminidase H

PDB Structure

PDB 1C90
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Mutations of endo-beta-N-acetylglucosaminidase H active site residues Assp130 and Glu132: activities and conformations.
Rao, V., Cui, T., Guan, C., Van Roey, P.
Protein Sci.