CATH Classification

Domain Context

CATH Clusters

Superfamily Dihydrodipicolinate Reductase; domain 2
Functional Family

Enzyme Information

1.2.1.59
Glyceraldehyde-3-phosphate dehydrogenase (NAD(P)(+)) (phosphorylating).
based on mapping to UniProt P39460
D-glyceraldehyde 3-phosphate + phosphate + NAD(P)(+) = 3-phospho-D- glyceroyl phosphate + NAD(P)H.
-!- NAD(+) and NADP(+) can be used as cofactors with similar efficiency, unlike EC 1.2.1.12 and EC 1.2.1.13, which are NAD(+)- and NADP(+)- dependent, respectively.

UniProtKB Entries (1)

P39460
G3P_SACS2
Saccharolobus solfataricus P2
Glyceraldehyde-3-phosphate dehydrogenase

PDB Structure

PDB 1B7G
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of the glyceraldehyde-3-phosphate dehydrogenase from the hyperthermophilic archaeon Sulfolobus solfataricus.
Isupov, M.N., Fleming, T.M., Dalby, A.R., Crowhurst, G.S., Bourne, P.C., Littlechild, J.A.
J.Mol.Biol.