CATH Classification

Domain Context

CATH Clusters

Superfamily SH3 Domains
Functional Family

Enzyme Information

2.7.10.2
Non-specific protein-tyrosine kinase.
based on mapping to UniProt Q06187
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
-!- Unlike EC 2.7.10.1, this protein-tyrosine kinase does not have a transmembrane domain. -!- In the human genome, 32 non-specific protein-tyrosine kinases have been identified and these can be divided into 10 families. -!- Formerly EC 2.7.1.112.

UniProtKB Entries (1)

Q06187
BTK_HUMAN
Homo sapiens
Tyrosine-protein kinase BTK

PDB Structure

PDB 1AWW
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
Solution structure of the SH3 domain from Bruton's tyrosine kinase.
Hansson, H., Mattsson, P.T., Allard, P., Haapaniemi, P., Vihinen, M., Smith, C.I., Hard, T.
Biochemistry