CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family DNA polymerase III subunit delta

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt P28631
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

P28631
HOLB_ECOLI
Escherichia coli K-12
DNA polymerase III subunit delta'

PDB Structure

PDB 1A5T
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of the delta' subunit of the clamp-loader complex of E. coli DNA polymerase III.
Guenther, B., Onrust, R., Sali, A., O'Donnell, M., Kuriyan, J.
Cell(Cambridge,Mass.)