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PDB Information
| PDB | 6C2Y |
| Method | X-RAY DIFFRACTION |
| Host Organism | Spodoptera aff. frugiperda 2 RZ-2014 |
| Gene Source | Homo sapiens |
| Primary Citation |
Utilizing a structure-based docking approach to develop potent G protein-coupled receptor kinase (GRK) 2 and 5 inhibitors.
Waldschmidt, H.V., Bouley, R., Kirchhoff, P.D., Lee, P., Tesmer, J.J.G., Larsen, S.D.
Bioorg. Med. Chem. Lett.
|
| Header | Transferase/Signaling Protein |
| Released | 2018-01-09 |
| Resolution | 2.740 |
| CATH Insert Date | 03 Jun, 2018 |
PDB Images (11)
6c2yA01
CATH Domain 6c2yA01
6c2yA02
CATH Domain 6c2yA02
6c2yA03
CATH Domain 6c2yA03
6c2yA04
CATH Domain 6c2yA04
6c2yA05
CATH Domain 6c2yA05
6c2yB00
CATH Domain 6c2yB00
6c2yG00
CATH Domain 6c2yG00
PDB Chains (3)
| Chain ID | Date inserted into CATH | CATH Status |
| A | 03 Jun, 2018 | Chopped
|
| B | 03 Jun, 2018 | Chopped
|
| G | 03 Jun, 2018 | Chopped
|
CATH Domains (7)
UniProtKB Entries (3)
| Accession |
Gene ID |
Taxon |
Description |
| P62871 |
GBB1_BOVIN |
Bos taurus |
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 |
| P25098 |
ARBK1_HUMAN |
Homo sapiens |
Beta-adrenergic receptor kinase 1 |
| P63212 |
GBG2_BOVIN |
Bos taurus |
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 |