PDB 5uum

PDB Links
Overview

PDB Information

PDB	5UUM
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Epistatic mutations in PUMA BH3 drive an alternate binding mode to potently and selectively inhibit anti-apoptotic Bfl-1. Jenson, J.M., Ryan, J.A., Grant, R.A., Letai, A., Keating, A.E. Elife
Header	Apoptosis
Released	2017-02-17
Resolution	2.350
CATH Insert Date	14 Nov, 2017

PDB Images (7)

Image of CATH 5uum

5uum

PDB 5uum

Image of CATH 5uumA

5uumA

PDB Chain 5uumA

Image of CATH 5uumB

5uumB

PDB Chain 5uumB

Image of CATH 5uumC

5uumC

PDB Chain 5uumC

Image of CATH 5uumD

5uumD

PDB Chain 5uumD

Image of CATH 5uumA01

5uumA01

CATH Domain 5uumA01

Image of CATH 5uumB01

5uumB01

CATH Domain 5uumB01

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	14 Nov, 2017	Chopped
B	14 Nov, 2017	Chopped
C	14 Nov, 2017	Rejected
D	14 Nov, 2017	Rejected

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5uumA01	10 Dec, 2017	1.10.437.10	Assigned
5uumB01	10 Dec, 2017	1.10.437.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q07820	MCL1_HUMAN	Homo sapiens	Induced myeloid leukemia cell differentiation protein Mcl-1
Q07820	MCL1_HUMAN	Homo sapiens	Induced myeloid leukemia cell differentiation protein Mcl-1