PDB Information

PDB5U7R
MethodX-RAY DIFFRACTION
Host Organismunidentified baculovirus
Gene SourceHomo sapiens
Primary Citation
Identification of a new class of potent Cdc7 inhibitors designed by putative pharmacophore model: Synthesis and biological evaluation of 2,3-dihydrothieno[3,2-d]pyrimidin-4(1H)-ones.
Kurasawa, O., Oguro, Y., Miyazaki, T., Homma, M., Mori, K., Iwai, K., Hara, H., Skene, R., Hoffman, I., Ohashi, A., Yoshida, S., Ishikawa, T., Cho, N.
Bioorg. Med. Chem.
HeaderTransferase
Released2016-12-12
Resolution3.330
CATH Insert Date07 May, 2017

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped
B 08 May, 2017 Chopped
C 08 May, 2017 Chopped
D 08 May, 2017 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
5u7rA01 07 Mar, 2018 3.30.200.20 Assigned
5u7rA02 07 Mar, 2018 1.10.510.10 Assigned
5u7rB01 07 Mar, 2018 3.30.200.20 Assigned
5u7rB02 07 Mar, 2018 1.10.510.10 Assigned
5u7rC01 07 Mar, 2018 3.30.200.20 Assigned
5u7rC02 07 Mar, 2018 1.10.510.10 Assigned
5u7rD01 07 Mar, 2018 3.30.200.20 Assigned
5u7rD02 07 Mar, 2018 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
O75116 ROCK2_HUMAN Homo sapiens Rho-associated protein kinase 2
O75116 ROCK2_HUMAN Homo sapiens Rho-associated protein kinase 2
O75116 ROCK2_HUMAN Homo sapiens Rho-associated protein kinase 2
O75116 ROCK2_HUMAN Homo sapiens Rho-associated protein kinase 2