PDB 5t0l

PDB Links
Overview

PDB Information

PDB	5T0L
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Toxoplasma gondii
Primary Citation	Discovery of Potent and Selective Leads against Toxoplasma gondii Dihydrofolate Reductase via Structure-Based Design. Welsch, M.E., Zhou, J., Gao, Y., Yan, Y., Porter, G., Agnihotri, G., Li, Y., Lu, H., Chen, Z., Thomas, S.B. ACS Med Chem Lett
Header	Oxidoreductase/Oxidoreductase Inhibitor
Released	2016-08-16
Resolution	3.130
CATH Insert Date	09 Oct, 2016

PDB Images (6)

Image of CATH 5t0l

5t0l

PDB 5t0l

Image of CATH 5t0lA

5t0lA

PDB Chain 5t0lA

Image of CATH 5t0lB

5t0lB

PDB Chain 5t0lB

Image of CATH 5t0lB01

5t0lB01

CATH Domain 5t0lB01

Image of CATH 5t0lB02

5t0lB02

CATH Domain 5t0lB02

Image of CATH 5t0lB03

5t0lB03

CATH Domain 5t0lB03

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	10 Oct, 2016	Domchop review
B	10 Oct, 2016	Chopped

CATH Domains (3)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5t0lB01	13 Oct, 2016	3.40.430.10	Assigned
5t0lB02	13 Oct, 2016		Holding pen
5t0lB03	13 Oct, 2016	3.30.572.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q07422	DRTS_TOXGO	Toxoplasma gondii	Bifunctional dihydrofolate reductase-thymidylate synthase
Q07422	DRTS_TOXGO	Toxoplasma gondii	Bifunctional dihydrofolate reductase-thymidylate synthase