PDB 5lqf

PDB Information

PDB5LQF
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Cyclin-Dependent Kinase (CDK) Inhibitors: Structure-Activity Relationships and Insights into the CDK-2 Selectivity of 6-Substituted 2-Arylaminopurines.
Coxon, C.R., Anscombe, E., Harnor, S.J., Martin, M.P., Carbain, B., Golding, B.T., Hardcastle, I.R., Harlow, L.K., Korolchuk, S., Matheson, C.J., Newell, D.R., Noble, M.E., Sivaprakasam, M., Tudhope, S.J., Turner, D.M., Wang, L.Z., Wedge, S.R., Wong, C., Griffin, R.J., Endicott, J.A., Cano, C.
J. Med. Chem.
HeaderTransferase
Released2016-08-17
Resolution2.060
CATH Insert Date07 May, 2017

PDB Images (17)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped
B 08 May, 2017 Chopped
C 08 May, 2017 Chopped
D 08 May, 2017 Chopped
E 08 May, 2017 Chopped
F 08 May, 2017 Chopped

CATH Domains (10)

Domain ID Date inserted into CATH Superfamily CATH Status
5lqfA01 15 May, 2017 3.30.200.20 Assigned
5lqfA02 15 May, 2017 1.10.510.10 Assigned
5lqfB01 15 May, 2017 1.10.472.10 Assigned
5lqfB02 15 May, 2017 1.10.472.10 Assigned
5lqfC00 15 May, 2017 3.30.170.10 Assigned
5lqfD01 15 May, 2017 3.30.200.20 Assigned
5lqfD02 15 May, 2017 1.10.510.10 Assigned
5lqfE01 15 May, 2017 1.10.472.10 Assigned
5lqfE02 15 May, 2017 1.10.472.10 Assigned
5lqfF00 15 May, 2017 3.30.170.10 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
P33552 CKS2_HUMAN Homo sapiens Cyclin-dependent kinases regulatory subunit 2
P14635 CCNB1_HUMAN Homo sapiens G2/mitotic-specific cyclin-B1
P14635 CCNB1_HUMAN Homo sapiens G2/mitotic-specific cyclin-B1
P33552 CKS2_HUMAN Homo sapiens Cyclin-dependent kinases regulatory subunit 2
P06493 CDK1_HUMAN Homo sapiens Cyclin-dependent kinase 1
P06493 CDK1_HUMAN Homo sapiens Cyclin-dependent kinase 1