CATH Domain 5lqfF00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.170	Cyclin-Dependent Kinase Subunit Type 2
	3.30.170.10	Cyclin-dependent kinase, regulatory subunit

Domain Context

CATH Clusters

Superfamily	Cyclin-dependent kinase, regulatory subunit
Functional Family	Cyclin-dependent kinases regulatory subunit

Enzyme Information

UniProtKB Entries (1)

CCNB1_HUMAN

Homo sapiens

G2/mitotic-specific cyclin-B1

PDB Structure

PDB	5LQF
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Cyclin-Dependent Kinase (CDK) Inhibitors: Structure-Activity Relationships and Insights into the CDK-2 Selectivity of 6-Substituted 2-Arylaminopurines. Coxon, C.R., Anscombe, E., Harnor, S.J., Martin, M.P., Carbain, B., Golding, B.T., Hardcastle, I.R., Harlow, L.K., Korolchuk, S., Matheson, C.J., Newell, D.R., Noble, M.E., Sivaprakasam, M., Tudhope, S.J., Turner, D.M., Wang, L.Z., Wedge, S.R., Wong, C., Griffin, R.J., Endicott, J.A., Cano, C. J. Med. Chem.