PDB 5hq8

PDB Information

PDB5HQ8
MethodX-RAY DIFFRACTION
Host Organismunidentified baculovirus
Gene SourceHomo sapiens
Primary Citation
Structure-Based Design of a Novel SMYD3 Inhibitor that Bridges the SAM-and MEKK2-Binding Pockets.
Van Aller, G.S., Graves, A.P., Elkins, P.A., Bonnette, W.G., McDevitt, P.J., Zappacosta, F., Annan, R.S., Dean, T.W., Su, D.S., Carpenter, C.L., Mohammad, H.P., Kruger, R.G.
Structure
HeaderTransferase
Released2016-01-21
Resolution1.720
CATH Insert Date10 Apr, 2016

PDB Images (15)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 11 Apr, 2016 Chopped
B 11 Apr, 2016 Chopped
I 11 Apr, 2016 Rejected
J 11 Apr, 2016 Rejected

CATH Domains (10)

Domain ID Date inserted into CATH Superfamily CATH Status
5hq8A01 14 May, 2016 2.170.270.10 Assigned
5hq8A02 14 May, 2016 6.10.140.2220 Assigned
5hq8A03 14 May, 2016 1.10.220.160 Assigned
5hq8A04 14 May, 2016 1.25.40.970 Assigned
5hq8A05 14 May, 2016 1.25.40.10 Assigned
5hq8B01 14 May, 2016 2.170.270.10 Assigned
5hq8B02 14 May, 2016 6.10.140.2220 Assigned
5hq8B03 14 May, 2016 1.10.220.160 Assigned
5hq8B04 14 May, 2016 1.25.40.970 Assigned
5hq8B05 14 May, 2016 1.25.40.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q9Y2U5 M3K2_HUMAN Homo sapiens Mitogen-activated protein kinase kinase kinase 2
Q9Y2U5 M3K2_HUMAN Homo sapiens Mitogen-activated protein kinase kinase kinase 2
Q9H7B4 SMYD3_HUMAN Homo sapiens Histone-lysine N-methyltransferase SMYD3
Q9H7B4 SMYD3_HUMAN Homo sapiens Histone-lysine N-methyltransferase SMYD3