PDB 5hi4

PDB Information

PDB5HI4
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists.
Liu, S., Dakin, L.A., Xing, L., Withka, J.M., Sahasrabudhe, P.V., Li, W., Banker, M.E., Balbo, P., Shanker, S., Chrunyk, B.A., Guo, Z., Chen, J.M., Young, J.A., Bai, G., Starr, J.T., Wright, S.W., Bussenius, J., Tan, S., Gopalsamy, A., Lefker, B.A., Vincent, F., Jones, L.H., Xu, H., Hoth, L.R., Geoghegan, K.F., Qiu, X., Bunnage, M.E., Thorarensen, A.
Sci Rep
HeaderImmune System/Inhibitor
Released2016-01-11
Resolution1.800
CATH Insert Date02 Oct, 2016

PDB Images (18)

PDB Prints

PDB Chains (7)

Chain ID Date inserted into CATH CATH Status
A 03 Oct, 2016 Chopped
B 03 Oct, 2016 Chopped
C 03 Oct, 2016 Chopped
D 03 Oct, 2016 Chopped
H 03 Oct, 2016 Chopped
I 03 Oct, 2016 Rejected
L 03 Oct, 2016 Chopped

CATH Domains (10)

Domain ID Date inserted into CATH Superfamily CATH Status
5hi4A00 07 Oct, 2016 2.10.90.10 Assigned
5hi4B00 07 Oct, 2016 2.10.90.10 Assigned
5hi4C01 07 Oct, 2016 2.60.40.10 Assigned
5hi4C02 07 Oct, 2016 2.60.40.10 Assigned
5hi4D01 07 Oct, 2016 2.60.40.10 Assigned
5hi4D02 07 Oct, 2016 2.60.40.10 Assigned
5hi4H01 07 Oct, 2016 2.60.40.10 Assigned
5hi4H02 07 Oct, 2016 2.60.40.10 Assigned
5hi4L01 07 Oct, 2016 2.60.40.10 Assigned
5hi4L02 07 Oct, 2016 2.60.40.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q16552 IL17_HUMAN Homo sapiens Interleukin-17A
Q16552 IL17_HUMAN Homo sapiens Interleukin-17A