CATH Classification

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family Immunoglobulin heavy constant gamma 1

Enzyme Information

UniProtKB Entries (1)

Q16552
IL17_HUMAN
Homo sapiens
Interleukin-17A

PDB Structure

PDB 5HI4
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists.
Liu, S., Dakin, L.A., Xing, L., Withka, J.M., Sahasrabudhe, P.V., Li, W., Banker, M.E., Balbo, P., Shanker, S., Chrunyk, B.A., Guo, Z., Chen, J.M., Young, J.A., Bai, G., Starr, J.T., Wright, S.W., Bussenius, J., Tan, S., Gopalsamy, A., Lefker, B.A., Vincent, F., Jones, L.H., Xu, H., Hoth, L.R., Geoghegan, K.F., Qiu, X., Bunnage, M.E., Thorarensen, A.
Sci Rep