PDB 5e95

PDB Information

PDB5E95
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Inhibition of RAS function through targeting an allosteric regulatory site.
Spencer-Smith, R., Koide, A., Zhou, Y., Eguchi, R.R., Sha, F., Gajwani, P., Santana, D., Gupta, A., Jacobs, M., Herrero-Garcia, E., Cobbert, J., Lavoie, H., Smith, M., Rajakulendran, T., Dowdell, E., Okur, M.N., Dementieva, I., Sicheri, F., Therrien, M., Hancock, J.F., Ikura, M., Koide, S., O'Bryan, J.P.
Nat. Chem. Biol.
HeaderSignaling Protein/Inhibitor
Released2015-10-14
Resolution1.400
CATH Insert Date20 Nov, 2016

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 21 Nov, 2016 Chopped
B 21 Nov, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5e95A00 24 Nov, 2016 3.40.50.300 Assigned
5e95B00 24 Nov, 2016 2.60.40.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P01112 RASH_HUMAN Homo sapiens GTPase HRas