CATH Classification

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family

Enzyme Information

UniProtKB Entries (1)

P01112
RASH_HUMAN
Homo sapiens
GTPase HRas

PDB Structure

PDB 5E95
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Inhibition of RAS function through targeting an allosteric regulatory site.
Spencer-Smith, R., Koide, A., Zhou, Y., Eguchi, R.R., Sha, F., Gajwani, P., Santana, D., Gupta, A., Jacobs, M., Herrero-Garcia, E., Cobbert, J., Lavoie, H., Smith, M., Rajakulendran, T., Dowdell, E., Okur, M.N., Dementieva, I., Sicheri, F., Therrien, M., Hancock, J.F., Ikura, M., Koide, S., O'Bryan, J.P.
Nat. Chem. Biol.