PDB 5aqn

PDB Information

PDB5AQN
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms.
Jones, A.M., Westwood, I.M., Osborne, J.D., Matthews, T.P., Cheeseman, M.D., Rowlands, M.G., Jeganathan, F., Burke, R., Lee, D., Kadi, N., Liu, M., Richards, M., McAndrew, C., Yahya, N., Dobson, S.E., Jones, K., Workman, P., Collins, I., van Montfort, R.L.
Sci Rep
HeaderChaperone
Released2015-09-22
Resolution2.450
CATH Insert Date16 Oct, 2016

PDB Images (22)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 17 Oct, 2016 Chopped
B 17 Oct, 2016 Chopped
C 17 Oct, 2016 Chopped
D 17 Oct, 2016 Chopped
E 17 Oct, 2016 Chopped
F 17 Oct, 2016 Chopped

CATH Domains (15)

Domain ID Date inserted into CATH Superfamily CATH Status
5aqnA01 25 Oct, 2016 3.30.420.40 Assigned
5aqnA02 25 Oct, 2016 3.30.30.30 Assigned
5aqnA03 25 Oct, 2016 3.30.420.40 Assigned
5aqnA04 25 Oct, 2016 3.90.640.10 Assigned
5aqnB00 22 Oct, 2016 1.20.58.120 Assigned
5aqnC01 25 Oct, 2016 3.30.420.40 Assigned
5aqnC02 25 Oct, 2016 3.30.30.30 Assigned
5aqnC03 25 Oct, 2016 3.30.420.40 Assigned
5aqnC04 25 Oct, 2016 3.90.640.10 Assigned
5aqnD00 22 Oct, 2016 1.20.58.120 Assigned
5aqnE01 25 Oct, 2016 3.30.420.40 Assigned
5aqnE02 25 Oct, 2016 3.30.30.30 Assigned
5aqnE03 25 Oct, 2016 3.30.420.40 Assigned
5aqnE04 25 Oct, 2016 3.90.640.10 Assigned
5aqnF00 22 Oct, 2016 1.20.58.120 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
Q99933 BAG1_HUMAN Homo sapiens BAG family molecular chaperone regulator 1
P11142 HSP7C_HUMAN Homo sapiens Heat shock cognate 71 kDa protein
Q99933 BAG1_HUMAN Homo sapiens BAG family molecular chaperone regulator 1
P11142 HSP7C_HUMAN Homo sapiens Heat shock cognate 71 kDa protein
Q99933 BAG1_HUMAN Homo sapiens BAG family molecular chaperone regulator 1
P11142 HSP7C_HUMAN Homo sapiens Heat shock cognate 71 kDa protein