PDB Information

PDB5AQF
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms.
Jones, A.M., Westwood, I.M., Osborne, J.D., Matthews, T.P., Cheeseman, M.D., Rowlands, M.G., Jeganathan, F., Burke, R., Lee, D., Kadi, N., Liu, M., Richards, M., McAndrew, C., Yahya, N., Dobson, S.E., Jones, K., Workman, P., Collins, I., van Montfort, R.L.
Sci Rep
HeaderChaperone
Released2015-09-22
Resolution1.880
CATH Insert Date06 Nov, 2016

PDB Images (15)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 07 Nov, 2016 Chopped
B 07 Nov, 2016 Chopped
C 07 Nov, 2016 Chopped
D 07 Nov, 2016 Chopped

CATH Domains (10)

Domain ID Date inserted into CATH Superfamily CATH Status
5aqfA01 10 Nov, 2016 3.30.420.40 Assigned
5aqfA02 10 Nov, 2016 3.30.30.30 Assigned
5aqfA03 10 Nov, 2016 3.30.420.40 Assigned
5aqfA04 10 Nov, 2016 3.90.640.10 Assigned
5aqfB00 10 Nov, 2016 1.20.58.120 Assigned
5aqfC01 10 Nov, 2016 3.30.420.40 Assigned
5aqfC02 10 Nov, 2016 3.30.30.30 Assigned
5aqfC03 10 Nov, 2016 3.30.420.40 Assigned
5aqfC04 10 Nov, 2016 3.90.640.10 Assigned
5aqfD00 10 Nov, 2016 1.20.58.120 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q99933 BAG1_HUMAN Homo sapiens BAG family molecular chaperone regulator 1
Q99933 BAG1_HUMAN Homo sapiens BAG family molecular chaperone regulator 1
P11142 HSP7C_HUMAN Homo sapiens Heat shock cognate 71 kDa protein
P11142 HSP7C_HUMAN Homo sapiens Heat shock cognate 71 kDa protein