PDB 4xr8

PDB Information

PDB4XR8
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli K-12
Gene SourceEscherichia coli
Primary Citation
Structure of the E6/E6AP/p53 complex required for HPV-mediated degradation of p53.
Martinez-Zapien, D., Ruiz, F.X., Poirson, J., Mitschler, A., Ramirez, J., Forster, A., Cousido-Siah, A., Masson, M., Pol, S.V., Podjarny, A., Trave, G., Zanier, K.
Nature
HeaderViral Protein/ Antitumor Protein
Released2015-01-20
Resolution2.250
CATH Insert Date10 Apr, 2016

PDB Images (13)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 11 Apr, 2016 Holding pen
B 11 Apr, 2016 Holding pen
C 11 Apr, 2016 Chopped
D 11 Apr, 2016 Chopped
F 11 Apr, 2016 Chopped
H 11 Apr, 2016 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
4xr8C00 30 Apr, 2016 2.60.40.720 Assigned
4xr8D00 30 Apr, 2016 2.60.40.720 Assigned
4xr8F01 30 Apr, 2016 3.30.240.40 Assigned
4xr8F02 30 Apr, 2016 3.30.240.40 Assigned
4xr8H01 29 Nov, 2016 3.30.240.40 Assigned
4xr8H02 29 Nov, 2016 3.30.240.40 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
Q05086 UBE3A_HUMAN Homo sapiens Ubiquitin-protein ligase E3A
P03126 VE6_HPV16 Human papillomavirus type 16 Protein E6
P03126 VE6_HPV16 Human papillomavirus type 16 Protein E6
P04637 P53_HUMAN Homo sapiens Cellular tumor antigen p53
P0AEX9 MALE_ECOLI Escherichia coli K-12 Maltose/maltodextrin-binding periplasmic protein
P0AEX9 MALE_ECOLI Escherichia coli K-12 Maltose/maltodextrin-binding periplasmic protein
P04637 P53_HUMAN Homo sapiens Cellular tumor antigen p53
Q05086 UBE3A_HUMAN Homo sapiens Ubiquitin-protein ligase E3A