CATH Classification

Domain Context

CATH Clusters

Superfamily 2.60.40.720
Functional Family Cellular tumor antigen p53

Enzyme Information

UniProtKB Entries (3)

P0AEX9
MALE_ECOLI
Escherichia coli K-12
Maltose/maltodextrin-binding periplasmic protein
Q05086
UBE3A_HUMAN
Homo sapiens
Ubiquitin-protein ligase E3A
P03126
VE6_HPV16
Human papillomavirus type 16
Protein E6

PDB Structure

PDB 4XR8
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of the E6/E6AP/p53 complex required for HPV-mediated degradation of p53.
Martinez-Zapien, D., Ruiz, F.X., Poirson, J., Mitschler, A., Ramirez, J., Forster, A., Cousido-Siah, A., Masson, M., Pol, S.V., Podjarny, A., Trave, G., Zanier, K.
Nature