PDB Information

PDB4XI3
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Biochemical and Structural Basis for Constitutive Activity and Reduced SERM Potency in Acquired SERM/AI Resistant Metastatic Breast Cancers via ESR1 Somatic Mutation
Fanning, S.W., Mayne, C.G., Toy, W., Carlson, K., Greene, B., Nowak, J., Walter, R., Panchamukhi, S., Tajhorshid, E., Nettles, K.W., Chandarlapaty, S., Katzenellenbogen, J., Greene, G.L.
To Be Published
HeaderSignaling Protein
Released2015-01-06
Resolution2.490
CATH Insert Date10 Apr, 2016

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 11 Apr, 2016 Chopped
B 11 Apr, 2016 Chopped
C 11 Apr, 2016 Chopped
D 11 Apr, 2016 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4xi3A00 29 Apr, 2016 1.10.565.10 Assigned
4xi3B00 29 Apr, 2016 1.10.565.10 Assigned
4xi3C00 29 Apr, 2016 1.10.565.10 Assigned
4xi3D00 29 Apr, 2016 1.10.565.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P03372 ESR1_HUMAN Homo sapiens Estrogen receptor
P03372 ESR1_HUMAN Homo sapiens Estrogen receptor
P03372 ESR1_HUMAN Homo sapiens Estrogen receptor
P03372 ESR1_HUMAN Homo sapiens Estrogen receptor