1 keywords

CATH Domain 4xi3A00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.565 Retinoid X Receptor
Homologous Superfamily 1.10.565.10 Retinoid X Receptor

Domain Context

CATH Clusters

Superfamily Retinoid X Receptor
Functional Family Estrogen receptor

Enzyme Information

UniProtKB Entries (1)

P03372
ESR1_HUMAN
Homo sapiens
Estrogen receptor

PDB Structure

PDB 4XI3
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Biochemical and Structural Basis for Constitutive Activity and Reduced SERM Potency in Acquired SERM/AI Resistant Metastatic Breast Cancers via ESR1 Somatic Mutation
Fanning, S.W., Mayne, C.G., Toy, W., Carlson, K., Greene, B., Nowak, J., Walter, R., Panchamukhi, S., Tajhorshid, E., Nettles, K.W., Chandarlapaty, S., Katzenellenbogen, J., Greene, G.L.
To Be Published