Synthesis and Pharmacological Characterization of C4-Disubstituted Analogs of 1S,2S,5R,6S-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylate: Identification of a Potent, Selective Metabotropic Glutamate Receptor Agonist and Determination of Agonist-Bound Human mGlu2 and mGlu3 Amino Terminal Domain Structures.
Monn, J.A., Prieto, L., Taboada, L., Pedregal, C., Hao, J., Reinhard, M.R., Henry, S.S., Goldsmith, P.J., Beadle, C.D., Walton, L., Man, T., Rudyk, H., Clark, B., Tupper, D., Baker, S.R., Lamas, C., Montero, C., Marcos, A., Blanco, J., Bures, M., Clawson, D.K., Atwell, S., Lu, F., Wang, J., Russell, M., Heinz, B.A., Wang, X., Carter, J.H., Xiang, C., Catlow, J.T., Swanson, S., Sanger, H., Broad, L.M., Johnson, M.P., Knopp, K.L., Simmons, R.M., Johnson, B.G., Shaw, D.B., McKinzie, D.L.
J.Med.Chem.