PDB 4x8g

PDB Information

PDB4X8G
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation.
Lewis, H.D., Liddle, J., Coote, J.E., Atkinson, S.J., Barker, M.D., Bax, B.D., Bicker, K.L., Bingham, R.P., Campbell, M., Chen, Y.H., Chung, C.W., Craggs, P.D., Davis, R.P., Eberhard, D., Joberty, G., Lind, K.E., Locke, K., Maller, C., Martinod, K., Patten, C., Polyakova, O., Rise, C.E., Rudiger, M., Sheppard, R.J., Slade, D.J., Thomas, P., Thorpe, J., Yao, G., Drewes, G., Wagner, D.D., Thompson, P.R., Prinjha, R.K., Wilson, D.M.
Nat.Chem.Biol.
HeaderHydrolase/Hydrolase Inhibitor
Released2014-12-10
Resolution3.290
CATH Insert Date28 Jun, 2015

PDB Images (5)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
4x8gA01 22 Jul, 2015 2.60.40.1860 Assigned
4x8gA02 22 Jul, 2015 2.60.40.1700 Assigned
4x8gA03 22 Jul, 2015 3.75.10.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q9UM07 PADI4_HUMAN Homo sapiens Protein-arginine deiminase type-4