PDB 4tyd

PDB Links
Overview

PDB Information

PDB	4TYD
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Hepatitis C virus (isolate 1)
Primary Citation	Structure-based design of a novel series of azetidine inhibitors of the hepatitis C virus NS3/4A serine protease. Parsy, C., Alexandre, F.R., Brandt, G., Caillet, C., Cappelle, S., Chaves, D., Convard, T., Derock, M., Gloux, D., Griffon, Y., Lallos, L., Leroy, F., Liuzzi, M., Loi, A.G., Moulat, L., Musiu, C., Rahali, H., Roques, V., Seifer, M., Standring, D., Surleraux, D. Bioorg.Med.Chem.Lett.
Header	Hydrolase
Released	2014-07-08
Resolution	2.840
CATH Insert Date	14 Sep, 2014

PDB Images (37)

4tyd

PDB 4tyd

4tydA

PDB Chain 4tydA

4tydB

PDB Chain 4tydB

4tydC

PDB Chain 4tydC

4tydD

PDB Chain 4tydD

4tydE

PDB Chain 4tydE

4tydF

PDB Chain 4tydF

4tydG

PDB Chain 4tydG

4tydH

PDB Chain 4tydH

4tydJ

PDB Chain 4tydJ

4tydK

PDB Chain 4tydK

4tydL

PDB Chain 4tydL

4tydM

PDB Chain 4tydM

4tydA01

CATH Domain 4tydA01

4tydA02

CATH Domain 4tydA02

4tydB01

CATH Domain 4tydB01

4tydB02

CATH Domain 4tydB02

4tydC01

CATH Domain 4tydC01

4tydC02

CATH Domain 4tydC02

4tydD01

CATH Domain 4tydD01

4tydD02

CATH Domain 4tydD02

4tydE01

CATH Domain 4tydE01

4tydE02

CATH Domain 4tydE02

4tydF01

CATH Domain 4tydF01

4tydF02

CATH Domain 4tydF02

4tydG01

CATH Domain 4tydG01

4tydG02

CATH Domain 4tydG02

4tydH01

CATH Domain 4tydH01

4tydH02

CATH Domain 4tydH02

4tydJ01

CATH Domain 4tydJ01

4tydJ02

CATH Domain 4tydJ02

4tydK01

CATH Domain 4tydK01

4tydK02

CATH Domain 4tydK02

4tydL01

CATH Domain 4tydL01

4tydL02

CATH Domain 4tydL02

4tydM01

CATH Domain 4tydM01

4tydM02

CATH Domain 4tydM02

PDB Prints

PDB Chains (12)

Chain ID	Date inserted into CATH	CATH Status
A	15 Sep, 2014	Chopped
B	15 Sep, 2014	Chopped
C	15 Sep, 2014	Chopped
D	15 Sep, 2014	Chopped
E	15 Sep, 2014	Chopped
F	15 Sep, 2014	Chopped
G	15 Sep, 2014	Chopped
H	15 Sep, 2014	Chopped
J	15 Sep, 2014	Chopped
K	15 Sep, 2014	Chopped
L	15 Sep, 2014	Chopped
M	15 Sep, 2014	Chopped

CATH Domains (24)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4tydA01	16 Sep, 2014	2.40.10.120	Assigned
4tydA02	16 Sep, 2014	2.40.10.10	Assigned
4tydB01	16 Sep, 2014	2.40.10.120	Assigned
4tydB02	16 Sep, 2014	2.40.10.10	Assigned
4tydC01	16 Sep, 2014	2.40.10.120	Assigned
4tydC02	16 Sep, 2014	2.40.10.10	Assigned
4tydD01	16 Sep, 2014	2.40.10.120	Assigned
4tydD02	16 Sep, 2014	2.40.10.10	Assigned
4tydE01	16 Sep, 2014	2.40.10.120	Assigned
4tydE02	16 Sep, 2014	2.40.10.10	Assigned
4tydF01	16 Sep, 2014	2.40.10.120	Assigned
4tydF02	16 Sep, 2014	2.40.10.10	Assigned
4tydG01	16 Sep, 2014	2.40.10.120	Assigned
4tydG02	16 Sep, 2014	2.40.10.10	Assigned
4tydH01	16 Sep, 2014	2.40.10.120	Assigned
4tydH02	16 Sep, 2014	2.40.10.10	Assigned
4tydJ01	16 Sep, 2014	2.40.10.120	Assigned
4tydJ02	16 Sep, 2014	2.40.10.10	Assigned
4tydK01	16 Sep, 2014	2.40.10.120	Assigned
4tydK02	16 Sep, 2014	2.40.10.10	Assigned
4tydL01	16 Sep, 2014	2.40.10.120	Assigned
4tydL02	16 Sep, 2014	2.40.10.10	Assigned
4tydM01	16 Sep, 2014	2.40.10.120	Assigned
4tydM02	16 Sep, 2014	2.40.10.10	Assigned

UniProtKB Entries (12)

Accession	Gene ID	Taxon	Description
Q0ZNA6	Q0ZNA6_9HEPC	Hepacivirus C	NS3 protease
Q0ZNA6	Q0ZNA6_9HEPC	Hepacivirus C	NS3 protease
Q0ZNA6	Q0ZNA6_9HEPC	Hepacivirus C	NS3 protease
Q0ZNA6	Q0ZNA6_9HEPC	Hepacivirus C	NS3 protease
Q0ZNA6	Q0ZNA6_9HEPC	Hepacivirus C	NS3 protease
Q0ZNA6	Q0ZNA6_9HEPC	Hepacivirus C	NS3 protease
Q0ZNA6	Q0ZNA6_9HEPC	Hepacivirus C	NS3 protease
Q0ZNA6	Q0ZNA6_9HEPC	Hepacivirus C	NS3 protease
Q0ZNA6	Q0ZNA6_9HEPC	Hepacivirus C	NS3 protease
Q0ZNA6	Q0ZNA6_9HEPC	Hepacivirus C	NS3 protease
Q0ZNA6	Q0ZNA6_9HEPC	Hepacivirus C	NS3 protease
Q0ZNA6	Q0ZNA6_9HEPC	Hepacivirus C	NS3 protease