PDB 4r7m

PDB Links
Overview

PDB Information

PDB	4R7M
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Plasmodium falciparum 3D7
Primary Citation	Two-Pronged Attack: Dual Inhibition of Plasmodium falciparum M1 and M17 Metalloaminopeptidases by a Novel Series of Hydroxamic Acid-Based Inhibitors. Mistry, S.N., Drinkwater, N., Ruggeri, C., Sivaraman, K.K., Loganathan, S., Fletcher, S., Drag, M., Paiardini, A., Avery, V.M., Scammells, P.J., McGowan, S. J.Med.Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2014-08-28
Resolution	2.850
CATH Insert Date	09 Nov, 2014

PDB Images (37)

4r7m

PDB 4r7m

4r7mA

PDB Chain 4r7mA

4r7mB

PDB Chain 4r7mB

4r7mC

PDB Chain 4r7mC

4r7mD

PDB Chain 4r7mD

4r7mE

PDB Chain 4r7mE

4r7mF

PDB Chain 4r7mF

4r7mG

PDB Chain 4r7mG

4r7mH

PDB Chain 4r7mH

4r7mI

PDB Chain 4r7mI

4r7mJ

PDB Chain 4r7mJ

4r7mK

PDB Chain 4r7mK

4r7mL

PDB Chain 4r7mL

4r7mA01

CATH Domain 4r7mA01

4r7mA02

CATH Domain 4r7mA02

4r7mB01

CATH Domain 4r7mB01

4r7mB02

CATH Domain 4r7mB02

4r7mC01

CATH Domain 4r7mC01

4r7mC02

CATH Domain 4r7mC02

4r7mD01

CATH Domain 4r7mD01

4r7mD02

CATH Domain 4r7mD02

4r7mE01

CATH Domain 4r7mE01

4r7mE02

CATH Domain 4r7mE02

4r7mF01

CATH Domain 4r7mF01

4r7mF02

CATH Domain 4r7mF02

4r7mG01

CATH Domain 4r7mG01

4r7mG02

CATH Domain 4r7mG02

4r7mH01

CATH Domain 4r7mH01

4r7mH02

CATH Domain 4r7mH02

4r7mI01

CATH Domain 4r7mI01

4r7mI02

CATH Domain 4r7mI02

4r7mJ01

CATH Domain 4r7mJ01

4r7mJ02

CATH Domain 4r7mJ02

4r7mK01

CATH Domain 4r7mK01

4r7mK02

CATH Domain 4r7mK02

4r7mL01

CATH Domain 4r7mL01

4r7mL02

CATH Domain 4r7mL02

PDB Prints

PDB Chains (12)

Chain ID	Date inserted into CATH	CATH Status
A	10 Nov, 2014	Chopped
B	10 Nov, 2014	Chopped
C	10 Nov, 2014	Chopped
D	10 Nov, 2014	Chopped
E	10 Nov, 2014	Chopped
F	10 Nov, 2014	Chopped
G	10 Nov, 2014	Chopped
H	10 Nov, 2014	Chopped
I	10 Nov, 2014	Chopped
J	10 Nov, 2014	Chopped
K	10 Nov, 2014	Chopped
L	10 Nov, 2014	Chopped

CATH Domains (24)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4r7mA01	14 Nov, 2014	3.40.220.10	Assigned
4r7mA02	14 Nov, 2014	3.40.630.10	Assigned
4r7mB01	14 Nov, 2014	3.40.220.10	Assigned
4r7mB02	14 Nov, 2014	3.40.630.10	Assigned
4r7mC01	14 Nov, 2014	3.40.220.10	Assigned
4r7mC02	14 Nov, 2014	3.40.630.10	Assigned
4r7mD01	14 Nov, 2014	3.40.220.10	Assigned
4r7mD02	14 Nov, 2014	3.40.630.10	Assigned
4r7mE01	14 Nov, 2014	3.40.220.10	Assigned
4r7mE02	14 Nov, 2014	3.40.630.10	Assigned
4r7mF01	14 Nov, 2014	3.40.220.10	Assigned
4r7mF02	14 Nov, 2014	3.40.630.10	Assigned
4r7mG01	14 Nov, 2014	3.40.220.10	Assigned
4r7mG02	14 Nov, 2014	3.40.630.10	Assigned
4r7mH01	14 Nov, 2014	3.40.220.10	Assigned
4r7mH02	14 Nov, 2014	3.40.630.10	Assigned
4r7mI01	14 Nov, 2014	3.40.220.10	Assigned
4r7mI02	14 Nov, 2014	3.40.630.10	Assigned
4r7mJ01	14 Nov, 2014	3.40.220.10	Assigned
4r7mJ02	14 Nov, 2014	3.40.630.10	Assigned
4r7mK01	14 Nov, 2014	3.40.220.10	Assigned
4r7mK02	14 Nov, 2014	3.40.630.10	Assigned
4r7mL01	14 Nov, 2014	3.40.220.10	Assigned
4r7mL02	14 Nov, 2014	3.40.630.10	Assigned

UniProtKB Entries (12)

Accession	Gene ID	Taxon	Description
Q8IL11	Q8IL11_PLAF7	Plasmodium falciparum 3D7	M17 leucyl aminopeptidase
Q8IL11	Q8IL11_PLAF7	Plasmodium falciparum 3D7	M17 leucyl aminopeptidase
Q8IL11	Q8IL11_PLAF7	Plasmodium falciparum 3D7	M17 leucyl aminopeptidase
Q8IL11	Q8IL11_PLAF7	Plasmodium falciparum 3D7	M17 leucyl aminopeptidase
Q8IL11	Q8IL11_PLAF7	Plasmodium falciparum 3D7	M17 leucyl aminopeptidase
Q8IL11	Q8IL11_PLAF7	Plasmodium falciparum 3D7	M17 leucyl aminopeptidase
Q8IL11	Q8IL11_PLAF7	Plasmodium falciparum 3D7	M17 leucyl aminopeptidase
Q8IL11	Q8IL11_PLAF7	Plasmodium falciparum 3D7	M17 leucyl aminopeptidase
Q8IL11	Q8IL11_PLAF7	Plasmodium falciparum 3D7	M17 leucyl aminopeptidase
Q8IL11	Q8IL11_PLAF7	Plasmodium falciparum 3D7	M17 leucyl aminopeptidase
Q8IL11	Q8IL11_PLAF7	Plasmodium falciparum 3D7	M17 leucyl aminopeptidase
Q8IL11	Q8IL11_PLAF7	Plasmodium falciparum 3D7	M17 leucyl aminopeptidase