CATH Classification

Domain Context

CATH Clusters

Superfamily Leucine Aminopeptidase, subunit E, domain 1
Functional Family M17 leucyl aminopeptidase

Enzyme Information

UniProtKB Entries (1)

Q8IL11
Q8IL11_PLAF7
Plasmodium falciparum 3D7
M17 leucyl aminopeptidase

PDB Structure

PDB 4R7M
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Two-Pronged Attack: Dual Inhibition of Plasmodium falciparum M1 and M17 Metalloaminopeptidases by a Novel Series of Hydroxamic Acid-Based Inhibitors.
Mistry, S.N., Drinkwater, N., Ruggeri, C., Sivaraman, K.K., Loganathan, S., Fletcher, S., Drag, M., Paiardini, A., Avery, V.M., Scammells, P.J., McGowan, S.
J.Med.Chem.