PDB 4o02

PDB Information

PDB4O02
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Atomic basis for the species-specific inhibition of alpha V integrins by monoclonal antibody 17E6 is revealed by the crystal structure of alpha V beta 3 ectodomain-17E6 Fab complex.
Mahalingam, B., Van Agthoven, J.F., Xiong, J.P., Alonso, J.L., Adair, B.D., Rui, X., Anand, S., Mehrbod, M., Mofrad, M.R., Burger, C., Goodman, S.L., Arnaout, M.A.
J.Biol.Chem.
HeaderProtein Binding
Released2013-12-13
Resolution3.610
CATH Insert Date06 Apr, 2014

PDB Images (19)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 07 Apr, 2014 Chopped
B 07 Apr, 2014 Chopped
H 07 Apr, 2014 Chopped
L 07 Apr, 2014 Chopped

CATH Domains (14)

Domain ID Date inserted into CATH Superfamily CATH Status
4o02A01 25 Apr, 2014 2.130.10.130 Assigned
4o02A02 25 Apr, 2014 2.60.40.1460 Assigned
4o02A03 25 Apr, 2014 2.60.40.1510 Assigned
4o02A04 25 Apr, 2014 2.60.40.1530 Assigned
4o02B01 25 Apr, 2014 Holding pen
4o02B02 25 Apr, 2014 2.60.40.1510 Assigned
4o02B03 25 Apr, 2014 3.40.50.410 Assigned
4o02B04 25 Apr, 2014 2.10.25.10 Assigned
4o02B05 25 Apr, 2014 2.10.25.10 Assigned
4o02B06 25 Apr, 2014 4.10.1240.30 Assigned
4o02H01 25 Apr, 2014 2.60.40.10 Assigned
4o02H02 25 Apr, 2014 2.60.40.10 Assigned
4o02L01 25 Apr, 2014 2.60.40.10 Assigned
4o02L02 25 Apr, 2014 2.60.40.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P06756 ITAV_HUMAN Homo sapiens Integrin alpha-V
P05106 ITB3_HUMAN Homo sapiens Integrin beta-3